Search results for "primary [cosmic radiation]"
showing 10 items of 1110 documents
The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2.
2015
The NG2 proteoglycan is characteristically expressed by oligodendrocyte progenitor cells (OPC) and also by aggressive brain tumours highly resistant to chemo- and radiation therapy. Oligodendrocyte-lineage cells are particularly sensitive to stress resulting in cell death in white matter after hypoxic or ischemic insults of premature infants and destruction of OPC in some types of Multiple Sclerosis lesions. Here we show that the NG2 proteoglycan binds OMI/HtrA2, a mitochondrial serine protease which is released from damaged mitochondria into the cytosol in response to stress. In the cytosol, OMI/HtrA2 initiates apoptosis by proteolytic degradation of anti-apoptotic factors. OPC in which NG…
What is the opinion of the family doctors on the optometry consultations of the Navarre Health Service?
2020
Esta carta crea un precedente en España, ya que por primera vez se muestra la percepción que tienen los médicos de familia sobre las tres consultas de optometría abiertas en el Servicio Navarro de Salud (Osasunbidea), transcurridos 10 años de la creación de la primera de ellas en 2006. Teniendo en cuenta que no todas las comunidades autónomas cuentan con estas consultas implementadas en el sistema sanitario, consideramos que este servicio es fundamental ponerlo en marcha y desarrollarlo en el resto de comunidades, para ofrecer al paciente una mejor atención primaria. Asociación Española de Optometristas Unidos
Exploring the Relationship Between the Acceptability of an InternetBased Intervention for Depression in Primary Care and Clinical Outcomes: Secondary…
2019
Background: Depression is one of the most prevalent psychological disorders worldwide. Although psychotherapy for depression is effective, there are barriers to its implementation in primary care in Spain. The use of the Internet has been shown to be a feasible solution. However, the acceptability of Internet-based interventions has not been studied sufficiently. Objective: To assess the acceptability of an Internet-based intervention (IBI) for depression in primary care, and explore the relationship between expectations and satisfaction and the improvement in the clinical variables in primary care patients receiving this intervention. Furthermore, it offers data about the effects of some s…
Improving quality and safety in nursing homes and home care: the study protocol of a mixed-methods research design to implement a leadership interven…
2018
IntroductionNursing homes and home care face challenges across different countries as people are living longer, often with chronic conditions. There is a lack of knowledge regarding implementation and impact of quality and safety interventions as most research evidence so far is generated in hospitals. Additionally, there is a lack of effective leadership tools for quality and safety improvement work in this context.Methods and analysisThe aim of the ‘Improving Quality and Safety in Primary Care—Implementing a Leadership Intervention in Nursing Homes and Homecare’ (SAFE-LEAD) study is to develop and evaluate a research-based leadership guide for managers to increase quality and safety compe…
Investigating the direct and indirect effects of a school-based leadership program for primary school students: Rationale and study protocol for the …
2023
Background Leadership is a valuable skill that can be taught in school, and which may have benefits within and beyond the classroom. Learning to Lead (L2L) is a student-led, primary school-based leadership program whereby older ‘peer leaders’ deliver a fundamental movement skills (FMS) program to younger ‘peers’ within their own school. Aim The aims of the study are to determine the efficacy of a peer-led FMS intervention on: (i) peer leaders’ (aged 10 to 12 years) leadership effectiveness (primary outcome), leadership self-efficacy, well-being, and time on-task in the classroom; (ii) peers’ (aged 8 to 10 years) physical activity levels, actual and perceived FMS competency, cardiorespirato…
LEARNING STYLES AND METACOGNITION
2014
In this paper we introduce the results of a research that involved 60 primary school pupils. Attention is drawn to a relevant issue in instructional research: the potential value to learners of metacognitive awareness. Some implications of these issues for learning styles research are then discussed. The purpose of this study was to investigate how students perceive learning and their learning styles preferences. Through a reflection on relations between the personalization of education and knowledge of learning styles, we will emphasize how the very important issue, for a teacher, is to create his own working knowledge on his students' learning styles, if he really wants effectively stimul…
DinosARs - Learning with the help of augmented reality
2019
Master's thesis Multimedia and Educational Technology MM500 - University of Agder 2019 A two-dimensional way of interacting with learning material has been the norm fora long time. We’ve read books, taken notes and been taught from a blackboard sinceyouth, and has for most of us worked out just fine, but we are all different. We havethose visual learners, those who learn through seeing things, auditory learners, thosewho learn best through hearing and kinesthetic learners, those who learn by doing.Augmented reality can provide many unique affordances that can deliver a learningexperience that can benefit all learning types. Augmented reality can utilize both vi-suals, sound, and interactivi…
Adaptive Whisking in Mice
2021
Rodents generate rhythmic whisking movements to explore their environment. Whisking trajectories, for one, appear as a fixed pattern of whisk cycles at 5-10 Hz driven by a brain stem central pattern generator. In contrast, whisking behavior is thought to be versatile and adaptable to behavioral goals. To begin to systematically investigate such behavioral adaptation, we established a whisking task, in which mice altered the trajectories of whisking in a goal-oriented fashion to gain rewards. Mice were trained to set the whisker to a defined starting position and generate a protraction movement across a virtual target (no touch-related tactile feedback). By ramping up target distance based o…
Life events and primary monosymptomatic nocturnal enuresis: A pediatric pilot study
2017
Introduction: The association between primary monosymptomatic nocturnal enuresis (PMNE) and behavioral disorders was highlighted frequently, suggesting psychiatric origin. On the other hand, there is no difference between the incidence of mental disorders in children with PMNE and controls, although the psychological genesis could provide additional secondary forms, in which the child might react to stressful events with the resumption of involuntary urination at night, with a possible alteration of bowel control due to a high vulnerability to stressors. The purpose of this study is assessing the stressful events of life in a sample of children with PMNE. Materials and methods: 56 subjects …
The feasibility and possible benefits of indoor exergames in primary school
2017
The purpose of this study is to identify the potential contribution of exergames to Primary schoolers, to define what exergames are and to classify them, as well as whether exergames could be an effective tool in physical education lessons from the point of view of students. Can exergames work as a spark to turn on the engine of physical activity practice? Will students acquire or even develop any motor skills by playing exergames that can be transferred into classical physical activities? The study was conducted with eight students of 6th grade in a Primary school in Finland. Students were selected randomly without asking prerequisites or gaming background. During spring season the group p…